Allergy & Asthma Center, PC

Welcome

Allergy & Asthma Center, P.C., is an allergy practice based in Eugene, Corvallis, and Roseburg, Oregon.

Our practice includes allergists:

Appointments are available in the following locations in Oregon:

An allergist is a physician trained to diagnose, treat, and manage asthma and allergies, whether they are related to or caused by foods, environmental factors (such as pollen), drugs, or topical substances. Conditions that an allergist commonly treats include the following:

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For your information, each month we feature a topic of interest to our readers. Please read our current Topic of the Month below. To read previous articles that we have featured, please visit our Topic of the Month page.


February 2015 Topic of the Month

Allergic rhinitis, sometimes referred to as hay fever, is an inflammatory disease that causes sneezing, itchy/watery eyes, itchy/runny nose, and congestion. For millions of sufferers, antihistamine and nasal corticosteroid medications provide temporary relief of symptoms. For others, allergy shots (subcutaneous immunotherapy or SCIT) are a treatment option that can provide long-term relief.

Allergy shot treatment involves two phases. The first phase involves frequent injections of increasing amounts of allergen extract. This is followed by a maintenance phase, during which the injections are given about once a month. Although allergy shots can be very effective at controlling symptoms of allergic rhinitis, the schedule can be difficult to maintain. Local reactions, for example swelling and itchiness at the injection site, are also common allergy shot side effects. In addition, severe allergic reactions can occur but are relatively uncommon; deaths have even been reported.

Another form of allergy immunotherapy called sublingual immunotherapy (SLIT) allergy tablets was recently approved in the United States. Rather than shots, allergy tablets involve administering the allergens in a liquid or tablet form under the tongue, generally on a daily basis.

What Are the Treatments the FDA Approved?

The U.S. Food and Drug Administration (FDA) recently approved three allergy tablet products. Two are directed at different kinds of grass pollen, and one is for short ragweed. The two grass pollen allergy tablets are Oralair® (Stallergenes), which has five kinds of northern grass pollen, and Grastek® (Merck), which has timothy grass pollen. The short ragweed allergy tablet is called Ragwitek® (Merck).

These three allergy tablets provide an additional option for the treatment of allergic rhinitis/rhinoconjunctivitis triggered by ragweed or timothy/northern grasses.

Effectiveness

SLIT (allergy tablets) is similar to SCIT (injections) in terms of the effectiveness of controlling allergy symptoms; and both have been shown to provide long-term improvement, even after the treatment has ended. However, the treatment is effective only for the allergen contained in SCIT or allergy tablets. If someone is allergic to ragweed and trees, the ragweed tablets/shots would help control only ragweed symptoms during the ragweed season.

Safety

Allergy tablets have a more favorable safety profile than SCIT, which is why it does not need to be given in a medical setting after the first dose. However, the FDA-approved product information of the three SLIT tablets includes a warning about the possibility of severe allergic reactions from SLIT and a recommendation that an epinephrine autoinjector be prescribed to patients receiving allergy tablets in the event a severe allergic reaction should occur.

Side Effects

The primary side effects of allergy tablets are local reactions, such as itching or burning of the mouth or lips, and less commonly, gastrointestinal symptoms. These reactions usually stop after a few days or a week.

SLIT Liquid Drops

There are currently no FDA-approved SLIT liquid (drops) formulations. The effectiveness of SLIT with U.S. allergen extract drops is still under investigation, and the effectiveness of mixtures of allergens is not known. There is a wide range of effective and ineffective doses of SLIT liquid formulations across the published literature and expert opinion has been that each formulation needs to prove its safe and effective dosing regimen.

Another important question is optimal starting time and schedule, i.e., is it best to start some time before the season (e.g., two or four months), or can it be started just as the season begins? Does it have to be administered all year long, or can it be given just before and during the season? The allergy tablets dosing regimen will clearly impact treatment costs, which will be greater than SCIT due to higher extract costs associated with daily dosing.

Reprinted with permission from the American Academy of Allergy Asthma & Immunology